ACoS (advertising cost of sales)
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ACoS is ad spend divided by the sales those ads produced. If $300 of ads drives $1,000 of attributed sales, ACoS is 30%.
In practice, Amazon Ads reports ACoS for every Sponsored Products and Sponsored Brands campaign, and it is the number most ad teams manage to. Walmart Connect and most other ad platforms report ROAS instead, which is the same ratio upside down: a 30% ACoS is a ROAS of about 3.3. ACoS on its own does not tell you whether an ad sale made money. For that, compare it with your break-even ACoS, which depends on your margin per unit. A product with a 25% margin before ads loses money on every ad sale above a 25% ACoS, however good the ROAS looks in a report.
Related: work out break-even ACoS per channel in the fee and margin calculator.